Does coq10 interfere with statin drugs?

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Rylee Jacobs asked a question: Does coq10 interfere with statin drugs?
Asked By: Rylee Jacobs
Date created: Sat, Jan 23, 2021 6:40 PM
Date updated: Fri, Sep 2, 2022 11:23 AM

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Video answer: Statin drugs and coq10

Statin drugs and coq10

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At this time, coenzyme Q10 isn't universally recommended for preventing side effects from cholesterol-lowering drugs known as statins. Examples of statins include: Atorvastatin (Lipitor) Fluvastatin (Lescol XL)

Video answer: The high concentration of cholesterol

The high concentration of cholesterol

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At this time, coenzyme Q10 isn't universally recommended for preventing side effects from cholesterol-lowering drugs known as statins. Examples of statins include: Atorvastatin (Lipitor)

Although serum levels of coenzyme Q10 routinely decrease with statin therapy, not all studies confirm the potential mitochondrial dysfunction induced by statins. In humans, Laaksonen et al 9 found no change in high-energy phosphate levels and coenzyme Q10 levels in muscle biopsies from patients before and after treatment with simvastatin, 20 mg/d for 6 months.

According to the Centers for Disease Control, statin drugs and other prescription drugs to lower cholesterol are the most commonly used drugs amount adults 45 and older during 2011 to 2014. However, a recent meta-analysis 1 adds serious support to the growing body of research that statins can deplete your body storage of CoQ10.

CoQ10 supplements can interact with some medications, including beta-blockers, some antidepressants, and chemotherapy drugs. Your doctor might need to change your statin dosage if you also take...

ATA: The answers to your questions are Yes, Yes, and No. Statin drugs disrupt the malevolent pathway in the human body that blocks the production of far more than just CoQ10, however if you’re old enough to having been prescribed Statin drugs you probably need CoQ10 anyway.

CoQ10 can be taken at the same time as statin medication. However, regular CoQ10 is fat-soluble, so it is best absorbed with foods that contain fats. Some statins are better absorbed when taken without food, so, if yours is one of them, it would be better to take CoQ10 separately with a meal that contains fats or oils (preferably unsaturated ...

Blood pressure medications-- In a clinical study of individuals taking blood pressure medications, including diltiazem (Cardizem), metoprolol (Lopressor or Toprol), enalapril (Vasotec), and nitroglycerin (Nitrostat or Nitrobid), CoQ10 supplementation allowed the individuals to take lower dosages of these drugs. This suggests that CoQ10 may enhance the effectiveness of certain blood pressure medications, but more research is needed to verify these results.

Statins block the enzyme responsible for cholesterol production (HMG CoA reductase) whereas magnesium speeds up or slows down the activity of that enzyme to create the right amount of cholesterol in the body. Statins also block CoQ10 production because it required the same enzyme (HMG CoA reductase).

Interference with production of Co-Q 10 by statin drugs is the most likely explanation. The heart is a muscle and it cannot work when deprived of Co-Q 10. Cardiologist Peter Langsjoen studied 20 patients with completely normal heart function.

If you take statins to improve your blood cholesterol levels, some supplements may interfere with the effectiveness of statins or increase your risk of side effects, some potentially life-threatening. Supplements to avoid when taking statins include antioxidants, red yeast rice and grapefruit seed extract.

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Video answer: Statin drugs: what you need to know!

Statin drugs: what you need to know!