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Dabigatran is in a class of anticoagulant medications called direct thrombin inhibitors. It works by preventing blood clots from forming in the body.
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Brand name: Pradaxa Drug class: Thrombin inhibitors. Medically reviewed by Sophia Entringer, PharmD. Last updated on Aug 3, 2020. Uses; Warnings; Dosage; What to avoid; Side effects; Interactions; What is Pradaxa? Pradaxa is an anticoagulant (thrombin inhibitor) that helps prevent the formation of blood clots.
Class 1: For patients with AF or atrial flutter <48-hour duration and with high risk of stroke, IV heparin or LMWH, or administration of a factor Xa or direct thrombin inhibitor, is recommended as...
Novel Oral Anticoagulants Class Review September 2013 (updated September 2014) Page 1 Drug Class Review: Target Specific Oral Anticoagulants Dabigatran (Pradaxa), Rivaroxaban (Xarelto), and Apixaban (Eliquis) September 2013 VHA Pharmacy Benefits Management Services, Medical Advisory Panel and VISN Pharmacist Executives OBJECTIVE
Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. It is used as an alternative to warfarin and does not require monitoring by blood tests.
Brand Name: Pradaxa Generic Name: Dabigatran Drug Class: Anticoagulants, Cardiovascular; Anticoagulants, Hematologic; Thrombin Inhibitors
Pradaxa (dabigatran etexilate) is an oral anticoagulant under development by Boehringer Ingelheim. Its primary indication is for prevention of venous thromboembolism (VTE) following orthopaedic surgery, such as operations for total hip and total knee replacement.
Pradaxa contains the active drug dabigatran, which is part of a drug class called direct thrombin inhibitors. (A class of drugs is a group of medications that work in a similar way.) Pradaxa is a...
In October 2015, the U.S. Food & Drug Administration approved a Pradaxa antidote called Praxbind (idarucizumab). The availability of the new antidote effectively stopped many of the Pradaxa lawsuits, though claims filed after the 2014 lawsuit payout but before Praxbind became available to the public could still have some validity.
Known as novel oral anticoagulants (NOACs), these drugs offered patients far more convenience and freedom than their predecessors. The first and most-prescribed drug in this class is Pradaxa (dabigatran etexilate mesylate), which is manufactured and marketed by Boehringer Ingelheim, Germany's second-largest drugmaker.
Now there are new drugs known as non-vitamin K antagonist oral anticoagulants (NOACs). The two anticoagulants at the forefront of the market are Pradaxa (dabigatran), made by Boehringer Ingelheim, and Xarelto (rivaroxaban), manufactured by Johnson & Johnson's Janssen Pharmaceuticals division.