Ral hiv drug?

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Janiya Mante asked a question: Ral hiv drug?
Asked By: Janiya Mante
Date created: Sat, Mar 27, 2021 9:27 AM
Date updated: Sat, Sep 17, 2022 12:20 PM

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Video answer: Hiv-1 viral kinetics during treatment with multiple drug classes by ruy ribeiro

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Raltegravir (RAL), sold under the brand name Isentress, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following potential exposure. It is taken by mouth.

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Raltegravir ( RAL ), sold under the brand name Isentress, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following potential exposure. It is taken by mouth.

No dosing modifications are recommended when RAL is coadministered with atazanavir/ritonavir (ATV/r) or tipranavir/ritonavir (TPV/r). However, RAL high-dose (HD) tablets should not be coadministered with TPV/r. In adults, an increased dose of RAL is recommended when it is coadministered with rifampin.

Raltegravir: in treatment-naive patients with HIV-1 infection.Drugs. 2010 Mar 26; 70(5): 631-42. Nguyen BY, Isaacs RD, Teppler H, et al. Raltegravir: the first HIV-1 integrase strand transfer inhibitor in the HIV armamentarium.

daily) and RAL (800 mg twice daily), with close monitoring. In the presence of rifabutin, no dose adjustment required. * TLD (Tenofovir 300 mg, Lamivudine 300 mg, Dolutegravir 50 mg fixed dose combination) can be used once daily in adolescents living with HIV weighting at least 30 kg. Annex 3. Dosages of ARV drugs

Three drugs of this class are currently approved for use in HIV-positive individuals: raltegravir (RAL), elvitegravir (EVG), and dolutegravir (DTG), while cabotegravir (CAB) and bictegravir (BIC) are currently in clinical trials. RAL and EVG have been successful in clinical settings but have relatively low genetic barriers to resistance.

Cabotegravir (CAB) intramuscular (IM) plus rilpivirine (RPV) IM are co-packaged into a single product and are coadministered as a complete regimen; therefore, the dosing recommendations and clinical comments reflect the combination of CAB IM and RPV IM treatments. Drug interaction studies were not conducted with either CAB IM or RPV IM.

RAL * in FDC with rilpivirine (also oral) ** Cabenuva is the US tradename: Current NRTIs (‘nukes’): lamivudine: Epivir: 3TC: emtricitabine: Emtriva: FTC: abacavir: Ziagen: ABC: tenofovir-DF: Viread: TDF (or TD) tenofovir alefenamide: TAF: TAF: Dual NRTIs (2-in1 pills) Kivexa (ABC+3TC) KVX: Truvada (TDF+FTC) TVD: Descovy (TAF+FTC) F/TAF: Combivir (AZT+3TC ) CBV: Old nukes (now rarely used)

prevention of mother-to-child transmission of HIV: PrEP: pre-exposure prophylaxis of HIV: RAL: raltegravir: RBV: ribavirin: RIF: rifampicin: RNA: ribonucleic acid: RTV: ritonavir: sd-NVP: single-dose nevirapine: TAM: thymidine analogue mutation: TB: tuberculosis: TDF: tenofovir disoproxil fumarate: TPV: tipranavir: UNAIDS: Joint United Nations Programme on HIV/AIDS: UNICEF

Panels of multi-drug resistant recombinant infectious molecular clones, donated to the NIH AIDS Reagent Program: NRTI, NNRTI, PI & RAL; REGA HIV-1 Subtyping Tool Version 3.0; HIV-1 drug reistance mutations for Point-Of-Care (POC) genotypic resistance tests; HIV-1 genetic variability program for POC genotypic drug resistance hybridization assays

ART is recommended for everyone with HIV, and people with HIV should start ART as soon as possible. People on ART take a combination of HIV medicines (called an HIV treatment regimen) every day. A person's initial HIV regimen generally includes three HIV medicines from at least two different HIV drug classes.

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