Rifampin drug class?

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Stanton Gislason asked a question: Rifampin drug class?
Asked By: Stanton Gislason
Date created: Thu, Feb 11, 2021 8:32 PM
Date updated: Mon, Sep 19, 2022 10:06 PM

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Rifampicin capsules | rifampicin 300mg | r cin capsules | r cin 300 mg | rifampin

Top best answers to the question «Rifampin drug class»

Rifampin is in a class of medications called antimycobacterials. It works by killing the bacteria that cause infection. Antibiotics such as rifampin will not work for colds, flu, or other viral infections.

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Rifampin is in a class of medications called antimycobacterials. It works by killing the bacteria that cause infection. Antibiotics such as rifampin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Rifampicin is a member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei) It has a role as an EC 2.7.7.6 (RNA polymerase) inhibitor, a DNA synthesis inhibitor, an antitubercular agent, a leprostatic drug, an Escherichia coli metabolite, a protein synthesis inhibitor, a neuroprotective agent, an angiogenesis inhibitor, a pregnane X receptor agonist and an ...

Rifampin is an antibiotic that is used to treat or prevent tuberculosis (TB). Rifampin may also be used to reduce certain bacteria in your nose and throat that could cause meningitis or other infections. Rifampin prevents you from spreading these bacteria to other people, but rifampin will not treat an active meningitis infection.

Rifampicin is a polyketide belonging to the chemical class of compounds termed ansamycins, so named because of their heterocyclic structure containing a naphthoquinone core spanned by an aliphatic ansa chain. The naphthoquinonic chromophore gives rifampicin its characteristic red-orange crystalline color.

Rifampicin induces microsomal enzymes of the liver and therefore accelerates metabolism of some drugs, beta blockers, calciferol, coumadins, cyclosporin, dapsone, diazepam, digitalis, hexobarbital, ketoconazole, methadone, oral contraceptive pills, oral hypoglycaemic agents, phenytoin, sulphasalazine, theophylline, some anti-arrhythmic drugs such as disopyramide, lorcainide, mexiletine, quinidine, and verapamil.

Rifampin is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.

Based on the IDSA clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis, rifampin (in combination with oral penicillin V or intramuscular benzathine penicillin G) is an effective and recommended treatment option in chronic carriers of group A Streptococcus [IDSA [Shulman 2012]].

Rifampin is a potent inducer of the hepatic isoenzyme CYP3A4; dasabuvir (minor), paritaprevir and ritonavir are substrates of this isoenzyme. Rifampin also induces CYP2D6 and CYP2C8, enzymes partially responsible for the metabolism of ritonavir and dasabuvir, respectively.

Rifampin belongs to the class of medicines called antibiotics and works to kill or prevent the growth of bacteria. However, it will not work for colds, flu, or other virus infections. Rifampin is available only with your doctor's prescription.

What are Rifamycin derivatives? Rifamycin derivatives are antibiotics that work by binding to and inhibiting the mycobacterial DNA dependent RNA polymerase. These antibiotics are bacteriocidal and therefore extremely effective antituberculosis agents, but resistance can develop rapidly if used as a single agent.

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