Video answer: Drug-resistant tb | infectious diseases | nclex-rn | khan academy
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The most common medications used to treat tuberculosis include: Isoniazid. Rifampin (Rifadin, Rimactane) Ethambutol (Myambutol)
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TB that is resistant to drugs is harder and more expensive to treat. TB disease can be treated by taking several drugs for 6 to 9 months. There are 10 drugs currently approved by the U.S. Food and Drug Administration (FDA) for treating TB. Of the approved drugs, the first-line anti-TB agents that form the core of treatment regimens are:
Generally anti TB drugs, that is TB medicine, is taken for the treatment of active TB or TB disease. One exception to this is when TB drugs are taken for the treatment of latent TB. One TB drug must never be taken on it’s own. Several TB drugs, or TB medication, must always be taken together.
Extensively Drug-Resistant Tuberculosis (XDR TB) - Options for Treatment Bedaquiline and Delamanid are new drugs. Ethambutol, Pyrazinamide, Thioamides, Cycloserine, Para-aminosalicylic acid, Streptomycin, and Clofazimine are possibly effective. Kanamycin, Capreomycin and Amikacin are injectable second-line.
For TB treatment the patient must take a combination of TB drugs. Now that drugs are available surgery is only occasionally used as treatment for TB. There are more than twenty drugs available for TB treatment. Which ones have to be taken depends on the circumstances of the patient.
The bacteria that cause tuberculosis (TB) can develop resistance to the antimicrobial drugs used to cure the disease. Multidrug-resistant TB (MDR-TB) is TB that does not respond to at least isoniazid and rifampicin, the 2 most powerful anti-TB drugs.
TB Alliance (The Global Alliance for TB Drug Development, Inc.) is a not-for-profit organization dedicated to finding faster-acting and affordable drug regimens to fight TB. Through innovative science and with partners around the globe, we aim to ensure equitable access to faster, better TB cures that will advance global health and prosperity.
In India, TB is a major public health issue with an estimated prevalence of 256 per 100,000 population and 26 per 100,000 population dying of TB.1Although about 85% of TB cases are successfully treated, treatment-related adverse events including hepatotoxicity, skin reactions, gastrointestinal and neurological disorders account for significant morbidity leading to reduced effectiveness of therapy.
11 TB Modelling Group, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. 12 Global Alliance for TB Drug Development, New York, USA. 13 Present address: United States Agency for International Development, Washington, DC, USA.
Several new drugs have emerged recently as potential candidates for the treatment of TB. In most cases, their mechanism of action is distinct from that of the classical anti-TB drugs, although strains resistant to several of the novel drugs already have been described even prior to their routine clinical use. 4.1 Nitroimidazoles
The standard "short" course treatment for TB is isoniazid (along with pyridoxal phosphate to obviate peripheral neuropathy caused by isoniazid), rifampicin (also known as rifampin in the United States), pyrazinamide, and ethambutol for two months, then isoniazid and rifampicin alone for a further four months.