What's the half life of a thyroid medication?

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Nickolas Beer asked a question: What's the half life of a thyroid medication?
Asked By: Nickolas Beer
Date created: Tue, Mar 23, 2021 11:53 AM
Date updated: Sun, Jun 26, 2022 2:57 AM

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Top best answers to the question «What's the half life of a thyroid medication»

  • Synthroid, because it is a T4 only thyroid medication, has a half-life of around 5-7 days (6). What does that mean? It means that it will take 5 half-lives for this medication to be nearly completely eliminated from your system.

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Mean effective half-life: 9 to 10 days. Time to maximum concentration: 2 to 3 hours. Time to steady state: 6 weeks. Accumulation ratio: N/A (drug does not accumulate in the body) Levothyroxine has an oral bioavailability of up to 80 percent, and the body more readily absorbs the drug when taken on an empty stomach.

However, a single dose of T3 will last about 24 hours in the body more or less, depending on an individual’s metabolism of it (6 hour half life X 4 half life cycles = about 6.25% left in the body after 24 hours). The same thing is true, by the way, of the endogenous T3 your thyroid gland makes. It also has a short half life, exactly the same as the medication does.

Next thing is that taking different doses of thyroid med on alternate days is something that is done with T4 meds because they have a half life of about one week, so it takes a while to build up. T3 meds have a half life of less than a day, so the effect is much faster.

Synthroid, because it is a T4 only thyroid medication, has a half-life of around 5-7 days (6). What does that mean? It means that it will take 5 half-lives for this medication to be nearly completely eliminated from your system. If you do the math (7 days x 5 half-lives) you find that Synthroid will be in your system for a total of about 35 days.

"The 'half life' of thyroid hormone (how long it stays in your system) means that if you give it daily there are minimal peaks and troughs (ups and downs) in its blood level," she says. "However, if you give a larger dose on a weekly basis there are big peaks and troughs.

However, without thyroid replacement medication, a person with overt hypothyroidism cannot function optimally and will suffer from the physical and mental symptoms of hypothyroidism. The half-life of levothyroxine is 6-7 days, which means it takes about 4-5 weeks for your body to rid itself of levothyroxine. Nonetheless, as synthetic T4 levels start to wane, you can begin to experience symptoms within the first week of not taking your medication.

One consideration is Armour Thyroid but not sure of it's side effects yet. He DID tell me though, that it's possible (not guaranteed) that if I stop all meds and wait 3 months or so, the other half of thyroid might strengthen and eventually I could go without any need for meds. Has anyone been told the same? Anyone actually done this successfully?

The half-life of the drug is useful in determining the dosing frequency. Drug Half-life (t1/2) is defined as the amount of time required for the drug concentration to be reduced to exactly half its initial concentration or amount in the blood. The half-life is the time required for half of the drug to be metabolized and eliminated from the body.

Side Effects of Thyroid Medication The most common side effect of taking levothyroxine is hair loss during the first few months, which is usually temporary. Other potential thyroid medication side effects are less common, but you should contact your doctor if you experience any of the following: Increased sweating; Mood swings/Irritability; Nervousness

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