Ziprasidone drug interactions?

Asia Kuhlman asked a question: Ziprasidone drug interactions?
Asked By: Asia Kuhlman
Date created: Wed, May 26, 2021 9:24 AM
Date updated: Tue, Nov 8, 2022 11:57 AM


Video answer: Pharmacology - antipsychotics (made easy)

Pharmacology - antipsychotics (made easy)

Top best answers to the question «Ziprasidone drug interactions»

Some products that may interact with this drug are: metoclopramide, saquinavir. Many drugs besides ziprasidone may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, moxifloxacin, pimozide, procainamide, quinidine, sotalol, tacrolimus, thioridazine, among others.

Video answer: Antipsychotics (neuroleptics)

Antipsychotics (neuroleptics)

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Does ZIPRASIDONE HCL Interact with other Medications? Severe Interactions . These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for ...

Medications known to have contraindicated interactions with ziprasidone oral. Brand Names Include: All generic drug interactions for ziprasidone oral (lists will include brand and generic names): 37 serious drug interactions. 544 significant drug interactions. 128 minor drug interactions.

Ziprasidone is heavily metabolized in the liver with less than 5% of the drug excreted unchanged in the urine. 3 The primary reductive pathway is catalyzed by aldehyde oxidase, while 2 other less prominent oxidative pathways are catalyzed by CYP3A4. 3 Ziprasidone is unlikely to interact with other medications metabolized by CYP3A4 since only 1/3 of the antipsychotic is metabolized by the CYP3A4 system. 3

Ziprasidone belongs to a class of drugs called atypical antipsychotics… drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe ...

Interactions; What is ziprasidone? Ziprasidone is an antipsychotic medicine. Ziprasidone oral is used to treat schizophrenia and the manic symptoms of bipolar disorder (manic depression). Ziprasidone injection is used to quickly treat agitation in people with schizophrenia. Ziprasidone may also be used for purposes not listed in this medication guide. Warnings. You should not use ziprasidone if you have a heart rhythm disorder, long QT syndrome, uncontrolled heart failure, or if you have ...

ziprasidone food. Moderate Food Interaction. Alcohol can increase the nervous system side effects of ziprasidone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with ziprasidone.

The following adverse reactions were the most commonly observed adverse reactions associated with the use of ziprasidone (incidence of 5% or greater) and not observed at an equivalent incidence among placebo-treated patients (ziprasidone incidence at least twice that for placebo): Schizophrenia trials (see Table 11)

ziprasidone + codeine avoid combo if antitussive use; otherwise, use alternative or monitor resp. rate, BP, serotonin syndrome sx, especially during initiation/titration; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, serotonin syndrome, severe hypotension (incl. orthostasis, syncope), severe constipation/paralytic ileus, other anticholinergic adverse ...

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